Precision in Practice for Advanced/Recurrent Endometrial Cancer: Harnessing the Power of Social Learning to Improve Patient Outcomes
 

PROVIDERSHIP
This educational activity is jointly provided by Albert Einstein College of Medicine-Montefiore Medical Center and Medical Logix, LLC.

Release Date: February 06, 2025

Expiration Date: February 06, 2026

ACKNOWLEDGEMENT OF FINANCIAL SUPPORT
This program is supported by medical education grants from Eisai Inc. and Merck Sharp & Dohme LLC.

STATEMENT OF NEED

Endometrial cancer is among the few cancers increasing in incidence and mortality in the United States. In its early stages, endometrial carcinoma has a five-year relative survival rate of 96%, but it decreases to 18% for those with metastases. Surprisingly, mortality has been increasing faster than incidence. This is attributed to increasing rates of advanced cancers, higher-risk histologies, and older age of first diagnosis. Yet, there have also been increases in diagnoses in women aged less than 50 years, based on Surveillance, Epidemiology, and End Results (SEER) program data.

While the incidence and mortality has been increasing across all racial groups, the rate of increase for Black women has been the steepest. Adjusting for the higher rate of hysterectomy in Black women compared with White women, the differing rates of this cancer in these groups exemplify this racial disparity.

These statistics demonstrate the need for new therapeutics and subsequent education on their use in this field. To improve clinical outcomes, clinicians treating patients for advanced/recurrent endometrial cancer need to understand biomarker testing and molecular classification of disease, newest guidelines on management, and the evidence underlying these recommendations. Along with this, clinicians must be aware of the most effective ways to manage possible adverse events. To these ends, this educational initiative will allow clinicians managing patients with advanced/recurrent endometrial cancer to learn and discuss the crucial points in diagnosing and managing these patients to best increase long-term survival.

EDUCATIONAL OBJECTIVES

At the conclusion of this digital small group educational experience, participants will demonstrate the ability to:

• • Employ recommended biomarker testing to the diagnosis and biomarker-directed treatment of advanced/recurrent endometrial cancers.
  • Integrate updated FIGO staging to the diagnosis and classification of endometrial cancers.
  • Incorporate recently published clinical data into management strategies for advanced/recurrent endometrial cancer.
  • Employ evidence- and guideline-based recommendations for the recognition and management of advanced and recurrent endometrial cancer using robust clinical cases.
  • Use best practices to identify and appropriately manage endometrial cancer irAEs.

TARGET AUDIENCE
This activity is intended to meet the educational needs of gynecologic oncologists, general oncologists, and oncology APPs involved in the care of patients with advanced/recurrent endometrial cancer.

FACULTY

Ken Lin, MD 
Assistant Professor
Gynecologic Oncology 
Montefiore Medical Park at Eastchester 
Bronx, NY

PLANNING COMMITTEE

Joshua Hwang, MD
Content Development
Medical Logix, LLC

CONTENT REVIEWER

Victor B. Hatcher, PhD
Research Director
Montefiore Medical Center
Associate Dean
Professor of Biochemistry and Medicine
Albert Einstein College of Medicine

DISCLOSURE OF FINANCIAL RELATIONSHIPS
The “Policy on Identification, Mitigation, and Disclosure of Relevant Financial Relationships” of Albert Einstein College of Medicine-Montefiore Medical Center requires that any individual in control of content, including faculty, participating in CME activities disclose to the audience all relevant financial relationships with ineligible companies* in the past 24 months. Any individual in control of content who refuses to disclose, or whose disclosed relationships prove to create a conflict of interest, will be recused.

Individuals with the absence of relevant financial relationships with ineligible companies will be disclosed to the audience.
 

All financial relationships of individuals in a position to control the content of this CME activity are identified and mitigated prior to the educational activity.
 

*The ACCME defines an ineligible company as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Faculty Disclosures

Ken Lin, MD has disclosed no relevant financial relationships with an ACCME-defined ineligible company in the last 24 months.
 

Joshua Hwang, MD has disclosed no relevant financial relationships with an ACCME-defined ineligible company in the last 24 months.

Content Reviewer

Victor B. Hatcher, PhD has disclosed no relevant financial relationships with an ACCME-defined ineligible company in the last 24 months.

ACCREDITATION STATEMENT

In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and Medical Logix, LLC. Albert Einstein College of Medicine-Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

CREDIT DESIGNATION STATEMENT
Albert Einstein College of Medicine-Montefiore Medical Center designates this other activity (blended live and enduring curriculum) for a maximum of 4.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 

Other Credits

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
 

American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.

American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) Program

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 4.75 Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

DISCLOSURE OF UNLABELED USE
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a clinician relative to diagnostic and treatment options for a specific patient’s medical condition.
 

DISCLAIMER
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Albert Einstein College of Medicine-Montefiore Medical Center, Medical Logix, LLC or Eisai Inc. and Merck Sharp & Dohme LLC. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
 

METHOD OF PARTICIPATION/INSTRUCTIONS ON HOW TO RECEIVE CREDIT

Estimated time to complete this activity: 4 hours and 45 minutes

To successfully earn credit for this activity, participants must achieve a minimum score of 70% or higher on the posttest. This passing score demonstrates sufficient mastery of the material covered and ensures that learners have engaged meaningfully with the content. Participants who do not initially achieve the required score will have the opportunity to review the material and retake the posttest as needed to meet this criterion.

If you are seeking credit, you must complete the evaluation at the conclusion of the activity. Your certificate can be printed immediately.

In order to collect the maximum amount of credit (4.75) available, you must complete all of the below:

Baseline and Final Self-Assessments: 0.5 each for a total of 1.0 hour
Four self-study modules: Total of 1.25 hour
Two live sessions: 0.75 each for a total of 1.5 hours
Two Group Challenges: 0.50 each for a total of 1.0 hour

PRIVACY STATEMENT
The Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development (Einstein-Montefiore) is committed to protecting the privacy of personal and professional information provided by participants and educational collaborators. Einstein-Montefiore does not share personally identifiable information with third parties without the individual’s explicit consent, except as required for reporting purposes to the ACCME. To ensure the security of collected information, Einstein-Montefiore employs physical, electronic, and procedural safeguards in compliance with federal regulations, effectively protecting against loss, misuse, or unauthorized alteration of the data.

COLLECTION AND USE OF YOUR PERSONAL INFORMATION
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, middle initial, degree, email address, address and phone number. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected, retained, and used by Einstein-Montefiore to continuously improve the learning experience. Einstein-Montefiore will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Einstein-Montefiore will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws.

CONTACT INFORMATION
For questions regarding CME credit, contact Albert Einstein College of Medicine-Montefiore Medical Center at cme@montefiore.org.

For technical questions related to this activity, please contact XX