Turning Complexity into Clarity in Chronic Immune-Mediated Neuropathies

Presented by: Johns Hopkins School University of Medicine

Release Date: August 31, 2023                                                                  

Expiration Date: August 31, 2024

Estimated time to complete this activity: 3 hours and 45 minutes. This activity has been approved for a maximum of 3.75 AMA PRA Category 1 Credits™.

Fees and Prerequisites: There are no fees or prerequisites.

Acknowledgement of Commercial Support: Supported by an independent educational grant from Takeda Pharmaceuticals U.S.A., Inc.

Target Audience

This activity is intended to meet the educational needs of neurologists, NPs, PA, Nurses and Infusion Specialists managing patients with CIDP and MMN.

Learning Objectives

 After participating in this activity, learners will demonstrate the ability to:

• Apply knowledge of the differential diagnosis of chronic immune-mediated neuropathies to the diagnosis of CIDP and MMN.
• Utilize international guidelines recommendations in the diagnostic workup of patients with CIDP and MMN.
• Incorporate updated clinical trial data of current and emerging IVIG, SCIG, and other immune modulators to the management of CIDP and MMN.
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Presented by the Johns Hopkins University School of Medicine

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Johns Hopkins University School of Medicine and Medical Logix, LLC. The Johns Hopkins University School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement 

The Johns Hopkins University School of Medicine designates this other/blended learning activity for a maximum of 3.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other Credits

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit^TM from organizations accredited by the ACCME.

American Association of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of PAs (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. PAs may receive a maximum of 3.75 AAPA Category 1 Credit for completing this program.

Statement of Need

Polyneuropathy may be defined broadly as the dysfunction of many or all nerves. Specifically, some of these polyneuropathies are mediated or caused by the immune system. These immune-mediated polyneuropathies can be acute, such as Guillain–Barré syndrome (GBS), or chronic, such as chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN). CIDP is a progressive immune-mediated disorder of the peripheral nerves attributed to demyelination and impairment of signal conduction in motor and/or sensory nerves. Symptoms include loss of strength and sensation typically causing symmetrical, proximal, and distal weakness. Disease progression is variable, with many patients experiencing chronic patterns of relapse and remission. MMN is a rare neuropathy characterized by progressive asymmetric weakness and atrophy without sensory abnormalities, a presentation similar to that of motor neuron disease. MMN is considered an immune-mediated disorder on the basis of its responsiveness to treatment with intravenous immune globulin (IVIG), its association with anti-GM1 antibodies, and inflammatory infiltrates on nerve biopsy. CIDP and MMN are complex diseases that are frequently misdiagnosed and have many treatment options. This collaborative social learning platform establishes a network of providers who can support each other locally, as well as those from different communities, with the goal of learning and sharing best practices that will improve outcomes for patients with CIDP and MMN.

Policy on Presenter and Provider Disclosure

It is the policy of the Johns Hopkins University School of Medicine that the presenter and provider globally disclose conflicts of interest. The Johns Hopkins University School of Medicine OCME has established policies in place that will identify and mitigate relevant conflicts of interest prior to this educational activity. Detailed disclosure will be made prior to presentation of the education.

Format and Method of Participation

Review this internet-based CME activity. To take the post-test, please click on the post-test button below the video window of the player which will take you to the Johns Hopkins School of Medicine’s website. If you already have registered for other programs at this website, simply enter the requested information when prompted. Otherwise, complete the registration form to begin the testing process. The information you enter here will be used to generate your CME certificate. Please complete all fields to ensure accurate registration. Complete the post-test and evaluation and attest to the amount of time spent in the activity. Upon receiving a score of 70% or above, print your CME certificate.

Full Disclosure Policy Affecting CME Activities

As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), Johns Hopkins School of Medicine Office of Continuing Medical Education (OCME) requires attested and signed global disclosure of the existence of all financial interests or relationships with ineligible companies from any individual in a position to control the content of a CME activity sponsored by OCME. The following relationships have been reported for this activity:

No one in a position to control the content of this educational activity has disclosed a relevant financial interest or relationship with an ineligible company. All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Note: Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

MITIGATION OF RELEVANT FINANCIAL RELATIONSHIPS

Johns Hopkins University adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Johns Hopkins Statement of Responsibility

The Johns Hopkins School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

Copyright

All rights reserved - The Johns Hopkins School of Medicine. No part of this program may be used or reproduced in any manner whatsoever without written permission except in the case of brief quotations embodied in articles or reviews.

Internet CME Policy

The Office of Continuing Medical Education (OCME) at the Johns Hopkins School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins School of Medicine OCME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. OCME at the Johns Hopkins School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins School of Medicine CME program. CME collects only the information necessary to provide you with the services that you request. 

Disclaimer

The opinions and recommendations expressed by faculty and other experts, whose input is included in this program are their own. This other/blended learning activity is produced for educational purposes only. Use of the Johns Hopkins School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

AMERICANS WITH DISABILITIES ACT

The Johns Hopkins School of Medicine fully complies with the legal requirements of the ADA and the rules and regulations thereof. Please notify us if you have any special needs.

Course Format – Method of Participation

This enduring material is expected to take approximately 3.75 hours to complete. Once the activity is completed, you must pass the post-test and complete the evaluation with attestation to receive CME credit. 

POST-TEST
A post-test will be conducted at the conclusion of the activity. A grade of at least 70% within three attempts is needed to receive CME credit.

Faculty

Brett Morrison M.D., Ph.D.
Associate Professor of Neurology
Division of Neuromuscular Medicine
Program Director of Neuromuscular Medicine Fellowship
Director of Inpatient Neurology Consult Service
Johns Hopkins School of Medicine
Baltimore, MD

Off-Label Discussion

There are no references to off-label/unapproved uses of products in this program.

Confidentiality Disclaimer for CME Activity Participant

I certify that I am participating in this Johns Hopkins School of Medicine activity for CME-accredited training and/or educational purposes.

I understand that while I am participating in this capacity, I may be exposed to "protected health information," as that term is defined and used in Hopkins policies and in the federal HIPAA privacy regulations (the “Privacy Regulations”). Protected health information is information about a person's health or treatment that identifies the person.

I pledge and agree to use and disclose any of this protected health information only for the training and/or educational purposes of my visit and to keep the information confidential. I agree not to post or discuss this protected health information, including pictures and/or videos, on any social media site (eg, Facebook, Twitter, etc.), in any electronic messaging program or through any portable electronic device.

I understand that I may direct to the Johns Hopkins Privacy Officer any questions I have about my obligations under this Confidentiality Pledge or under any of the Hopkins policies and procedures and applicable laws and regulations related to confidentiality. The contact information is:  Johns Hopkins Privacy Officer, telephone: 410-614-9900,

e-mail: HIPAA@jhmi.edu.

“The Office of Continuing Medical Education at the Johns Hopkins School of Medicine, as sponsor of this activity, has relayed information with the CME attendees/participants and certify that the visitor is here for training, education and/or observation purposes only.”

For CME questions, please contact the CME Office 410-955-2959 or email cmenet@jhmi.edu.

For CME Certificates, please call (410) 502-9636.

Johns Hopkins School of Medicine
Office of Continuing Medical Education
720 Rutland Avenue/ Turner 20
Baltimore, Maryland 21205-2195
Reviewed & Approved by: General Counsel, Johns Hopkins Medicine (4/1/03)
(Updated 4/09 and 3/14)